[Elenco soci]


Papallo Ida

Assegnista


Università degli Studi di Napoli Federico II
ida.papallo@unina.it

SCOPUS ID: 57210820437



Pubblicazioni scientifiche

[1] Ausiello P., Martorelli M., Papallo I., Gloria A., Montanari R., Richetta M., Lanzotti A., Optimal Design of Surface Functionally Graded Dental Implants with Improved Properties, Lecture Notes in Mechanical Engineering, 294-305, (2023). Abstract
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Abstract: Over the past years, a wide range of dental implants has been proposed. In general, the dentists may find the best solutions according to the specific needs of the patients. A variety of factors influences the level of osseointegration and, consequently, the anchorage of the implant to the bone. The stress transfer mechanism along the bone-implant interface depends upon the surface area of the bone-implant contact. Great efforts have been devoted to the design of 3D porous lattice structures with tailored architectural features in order to reduce the implant stiffness as well as to favour bone ingrowth, thus stabilizing the device. Accordingly, the aim of the current study was to provide further insight into the design criteria for dental implants. In particular, starting from a screw implant (Implant A), different concepts of dental implants were developed: i) Implants B1–B5, with lattice shell surrounding a solid core, without thread; ii) Implant C, with lattice structure; iii) Implant D as topography optimized implant. Finite element analysis on the several models of bone-implant provided interesting information in terms of stress distributions in cortical and trabecular bone. Some differences among the implants may be ascribed to the different design criteria.

Keywords: Dental implants | Design criteria | Finite element analysis | Lattice structure | Topography optimization | Topology optimization

[2] De Santis R., Papallo I., Onofrio I., Peluso V., Gallicchio V., Rega A., D'Antò V., Improta G., Catauro M., Gloria A., Russo T., Analyzing the Role of Magnetic Features in Additive Manufactured Scaffolds for Enhanced Bone Tissue Regeneration, Macromolecular Symposia, 396(1), (2021). Abstract
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Abstract: The concept of magnetic guidance has opened a wide range of perspectives in the field of tissue regeneration. Accordingly, the aim of the current research is to design magnetic responsive scaffolds for enhanced bone tissue regeneration. Specifically, magnetic nanocomposite scaffolds are additively manufactured using 3D fibre deposition technique. The mechanical and magnetic properties of the fabricated scaffolds are first assessed. The role of magnetic features on the biological performances is properly analyzed.

Keywords: bone tissue engineering | design for additive manufacturing | magnetic nanocomposite scaffolds | mechanical and functional properties

[3] De Santis R., Russo T., Rau J.V., Papallo I., Martorelli M., Gloria A., Design of 3d additively manufactured hybrid structures for cranioplasty, Materials, 14(1), 1-15, (2021). Abstract
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Abstract: A wide range of materials has been considered to repair cranial defects. In the field of cranioplasty, poly(methyl methacrylate) (PMMA)-based bone cements and modifications through the inclusion of copper doped tricalcium phosphate (Cu-TCP) particles have been already investigated. On the other hand, aliphatic polyesters such as poly (e-caprolactone) (PCL) and polylactic acid (PLA) have been frequently investigated to make scaffolds for cranial bone regeneration. Accordingly, the aim of the current research was to design and fabricate customized hybrid devices for the repair of large cranial defects integrating the reverse engineering approach with additive manufacturing, The hybrid device consisted of a 3D additive manufactured polyester porous structures infiltrated with PMMA/Cu-TCP (97.5/2.5 w/w) bone cement. Temperature profiles were first evaluated for 3D hybrid devices (PCL/PMMA, PLA/PMMA, PCL/PMMA/Cu-TCP and PLA/PMMA/Cu-TCP). Peak temperatures recorded for hybrid PCL/PMMA and PCL/PMMA/Cu-TCP were significantly lower than those found for the PLA-based ones. Virtual and physical models of customized devices for large cranial defect were developed to assess the feasibility of the proposed technical solutions. A theoretical analysis was preliminarily performed on the entire head model trying to simulate severe impact conditions for people with the customized hybrid device (PCL/PMMA/Cu-TCP) (i.e., a rigid sphere impacting the implant region of the head). Results from finite element analysis (FEA) provided information on the different components of the model.

Keywords: Composite bone cement for cranioplasty | Design for additive manufacturing | Finite element analysis | Reverse engineering | Temperature profile analysis

[4] Solari D., Papallo I., Ugga L., Cavallo L.M., Onofrio I., Cuocolo R., Improta G., Brunetti A., Martorelli M., Gloria A., Cappabianca P., Russo T., Novel concepts and strategies in skull base reconstruction after endoscopic endonasal surgery, Acta IMEKO, 9(4), 67-73, (2020). Abstract
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Abstract: Recently, a variety of craniofacial approaches has been adopted to enter the skull base, including the endonasal endoscopic technique. An effective watertight technique, the reconstruction can be performed using different materials, both autologous and non-autologous, individually or combined in a multilayer fashion. The current study focuses on the development of new advanced devices and techniques that help to reduce the postoperative cerebrospinal fluid leak rate. Additive manufacturing allows the design of devices with tailored structural and functional features, as well as injectable semi-interpenetrating polymer networks and composites; therefore, specific mechanical/rheological and injectability studies are valuable. Accordingly, we propose new additive manufactured and injectable devices.

Keywords: Additive manufacturing | CSF leakage | Design of injectable systems | Endoscopic endonasal surgery | Reverse engineering | Skull base reconstruction

[5] Fucile P., Onofrio I., Papallo I., Gallicchio V., Rega A., D'Antò V., Improta G., de Santis R., Gloria A., Russo T., Strategies for the design of additively manufactured nanocomposite scaffolds for hard tissue regeneration, Acta IMEKO, 9(4), 53-59, (2020). Abstract
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Abstract: Additive manufacturing represents a powerful tool for the direct fabrication of lightweight and porous structures with tuneable properties. In this study, a fused deposition modelling/3D fibre deposition technique was considered for designing 3D nanocomposite scaffolds with specific architectures and tailored biological, mechanical, and mass transport properties. 3D poly(ε-caprolactone) (PCL)/hydroxyapatite (HA) nanocomposite scaffolds were designed for bone tissue engineering. An optimisation design strategy for the additive manufacturing processes based on extrusion/injection methods was at first extended to the development of the PCL/HA scaffolds. Further insight into the effect of the process parameters on the mechanical properties and morphological features of the nanocomposite scaffolds was provided. The nanocomposite structures were analysed at different levels, and the possibility of designing 3D customised scaffolds for mandibular defect regeneration (i.e., symphysis and ramus) was also reported.

Keywords: Additive manufacturing | Design of Experiments | Nanocomposites | Reverse Engineering | Scaffold Design and Analysis

[6] Rocco N., Papallo I., Nava M.B., Catanuto G., Accurso A., Onofrio I., Oliviero O., Improta G., Speranza D., Domingos M., Russo T., de Santis R., Martorelli M., Gloria A., Additive manufacturing and technical strategies for improving outcomes in breast reconstructive surgery, Acta IMEKO, 9(4), 74-79, (2020). Abstract
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Abstract: It has been widely reported that breast reconstruction improves the quality of life of women who undergo mastectomy for breast cancer. This approach provides many psychological advantages. Today, different techniques are available for the breast oncoplastic surgeon that involve the use of breast implants and autologous tissues, also offering interesting results in terms of aesthetic and patient-reported outcomes. On the other hand, advanced technologies and design strategies (i.e. design for additive manufacturing, reverse engineering) may allow the development of customised porous structures with tailored morphological, mechanical, biological, and mass transport properties. For this reason, the current study deals with the challenges, principles, and methods of developing 3D additive manufactured structures in breast reconstructive surgery. Specifically, the aim was to design 3D additive manufactured poly(ε-caprolactone) scaffolds with different architectures (i.e. lay-down patterns). Preliminary mechanical and biological analyses have shown the effect of the lay-down pattern on the performances of the manufactured structures.

Keywords: Additive manufacturing | Breast reconstructive surgery | Fat grafting | Functional properties | Mechanical | Pore geometry and lay-down pattern | Reverse engineering | Scaffold design

[7] Solari D., Cavallo L.M., Cappabianca P., Onofrio I., Papallo I., Brunetti A., Ugga L., Cuocolo R., Gloria A., Improta G., Martorelli M., Russo T., Skull base reconstruction after endoscopic endonasal surgery: New strategies for raising the dam, 2019 IEEE International Workshop on Metrology for Industry 4.0 and IoT, MetroInd 4.0 and IoT 2019 - Proceedings, 28-32, (2019). Abstract
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Abstract: In the last decades a variety of innovative craniofacial approaches has been adopted to entire skull base. The endonasal endoscopic route has emerged as a suitable methodology for several skull base lesions. An effective watertight closure is essential to isolate the intracranial cavity in order to restore the natural intra and extradural compartment division, necessary to prevent postoperative cerebrospinal fluid (CSF) leakage and complications such as meningitis, brain herniation, and tension pneumocephalus. The reconstruction can be performed using different materials, both autologous (autologous grafts) and non-autologous, individually or combined in a multilayer fashion. The harvesting a nasoseptal flap is one of the most effective techniques: it reinforces the skull base closure granting isolation of the surgical field. The current study was focused on the development of new advanced devices and techniques, aiding in reducing postoperative CSF leak, which is one of the most feared complication of this surgical procedure. Additive manufacturing allows to design devices with tailored structural and functional features, in order to satisfy all the requirements. On the other hand, the development of injectable semi-IPNs and composites clearly benefits from specific mechanical/rheological and injectability studies. Accordingly, starting from some basic concepts, innovative principles and strategies were also proposed towards the design of additively manufactured and injectable devices.

Keywords: additive manufacturing | CSF leakage | design of injectable systems | endoscopic endonasal surgery | reverse engineering | skull base reconstruction

[8] Fucile P., Papallo I., Improta G., De Santis R., Gloria A., Onofrio I., D'Anto V., Maietta S., Russo T., Reverse Engineering and Additive Manufacturing towards the design of 3D advanced scaffolds for hard tissue regeneration, 2019 IEEE International Workshop on Metrology for Industry 4.0 and IoT, MetroInd 4.0 and IoT 2019 - Proceedings, 33-37, (2019). Abstract
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Abstract: 3D Printing and Additive Manufacturing technologies represent powerful tools for the direct fabrication of lightweight structures with improved and tunable properties. In current research, Fused Deposition Modeling (FDM)/3D fiber deposition technique was considered to design 3D multifunctional scaffolds with complex morphology, tailored biological, mechanical and mass transport properties. Polymeric and nanocomposite materials were used for scaffold design and optimization, with a particular focus on bone tissue engineering. As an example, poly(ϵ-caprolactone) (PCL), and PCL-based nanocomposite scaffolds were fabricated and analyzed. The effects of structural and morphological features (i.e., sequence of stacking, fiber spacing, pore size and geometry) as well as of nanoparticle inclusion on the mechanical performances were reported. Furthermore, the possibility to design 3D customized scaffolds for mandibular defect regeneration (i.e., symphysis and ramus) was also considered.

Keywords: Additive manufacturing | nanocomposites | reverse engineering | scaffold design

[9] Rocco N., Nava M.B., Catanuto G., Accurso A., Martorelli M., Oliviero O., Improta G., Papallo I., De Santis R., Gloria A., Speranza D., Additive manufacturing and tissue engineering to improve outcomes in breast reconstructive surgery, 2019 IEEE International Workshop on Metrology for Industry 4.0 and IoT, MetroInd 4.0 and IoT 2019 - Proceedings, 38-42, (2019). Abstract
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Abstract: Many women with early breast cancer undergo mastectomy as a consequence of an unfavorable tumor/breast ratio or because they prefer this option to breast conservation. As reported, breast reconstruction offers significant psychological advantages. Several techniques are currently available for the breast oncoplastic surgeon and offer interesting results in terms of aesthetic and patient-reported outcomes, using both breast implants and autologous tissues. On the other hand, advanced methodologies and technologies, such as reverse engineering and additive manufacturing, allow the development of customized porous scaffolds with tailored architectures, biological, mechanical and mass transport properties. Accordingly, the current research dealt with challenges, design methods and principles to develop 3D additively manufactured structures in breast reconstructive surgery.

Keywords: additive manufacturing | breast reconstructive surgery | design | fat grafting | reverse engineering | scaffold design